One of the most effective treatments for vitiligo is UVB narrow wave or band phototherapy, which stimulates the reserve of melanocytes and stabilises the de-pigmentation process.

Numerous studies have confirmed the results of phototherapy with NB ultraviolet UVB, which highlight that the results (visible in over 50% of the cases and especially in cases of focused or segmental vitiligo) occur after a year of treatment, for which it is common for patients to give up on the treatment before reaching this stage.

According to the results of a study performed in the Zagreb University Hospital, 57.9% of the patients that received a combined treatment of narrow-wave phototherapy and gel with superoxide dismutase for six months obtained over 50% of re-pigmentation, especially on the face and neck.

Vitiligo treatment with phototherapy

To improve results and to stimulate the re-pigmentation of the skin, the recommendation is to combine phototherapy with photo-sensitising agents and antioxidants, depending on the type of vitiligo.

In the case of vitiligo that affects areas with hair (arms, legs, etc.) a combination is recommended of photo-sensitising agents – both oral and topical – with phototherapy.

In the case of focal vitiligo, which affects localised areas such as the face, hands, etc. the combination of a gel with superoxide dismutase with phototherapy is recommended.

Pimecrolimus and UVB narrow band (311 nm) phototherapy in vitiligo. Gilda Zurita, Rodolfo Galán, Elio Ochoa, Enrique Uraga.
Treatment of Vitiligo with Narrow-Band UVB and Topical Gel Containing Catalase and Superoxide Dismutase. Kserimir Kostovic, Zrinjka Pastar,Aida Pasic, Romana Ceovic. Departamento de Dermatología del Hospital Universitario de Zagreb.


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